Research output per year
Research output per year
Personal profile
Research interests (short)
Extending psychiatric genomics to identify related and relevant biology
Biographical details
Following my undergraduate degree in Natural Sciences, I joined the Social, Genetic and Developmental Psychiatry (SGDP) Centre as a MSc+PhD student, working with Thalia Eley and Gerome Breen on genomic methods to study gene-environment interplay. As part of that, I performed the initial genome-wide association studies on cognitive behavioural therapy response in anxiety. I then joined Prof Breen's group as a postdoctoral researcher, working broadly in psychiatric genomics, but particularly on depression and its relationship to comorbid traits. Since January 2020, I am a Lecturer in Statistical Genetics at the SGDP, where I will focus on translating statistical genetic findings from psychiatric research to understand related and relevant biology.
Research interests
- The application of polygenic risk scores to biological phenotypes and to the study of individuals
- The integration of biological data to inform conclusions from statistical genetic methods
- The genetic epidemiology of psychiatric disorders, particularly post-traumatic stress disorder
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Genetic architecture distinguishes tinnitus from hearing loss
Clifford, R. E., Maihofer, A., Chatzinakos, C., Coleman, J. R. I., Daskalakis, N. P., Gasperi, M., Hogan, K., Mikita, E. A., Stein, M. B., Tcheandjieu, C., Telese, F., Zuo, Y., Ryan, A. F. & Nievergelt, C. M., 19 Jan 2024, In: Nature Communications. 15, 1, 614.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Investigating the genetic relationship between depression symptoms and Alzheimer’s Disease in clinically diagnosed and proxy cases
Gilchrist, L., Coleman, J., Howard, D., Adey, B., Davies, H. L., Mundy, J., ter Kuile, A., Davies, M., Bristow, S., Lee, S., Rogers, H., Curtis, C., Kalsi, G., Arathimos, R., Eley, T., Breen, G., Iacoangeli, A., Lewis, C. & Proitsi, P., 11 Sept 2024, (Accepted/In press) In: Nature Mental Health .Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure) -
Relative Age Effects on Attention-Deficit/Hyperactivity Disorder Symptoms and Educational Achievement: A Longitudinal UK Cohort Study
Deng, Q., Coleman, J. R. I., Mottershead, E., Ronald, A., Zavos, H. M. S. & Kuntsi, J., 5 Feb 2024, (E-pub ahead of print) In: Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) Open.Research output: Contribution to journal › Article › peer-review
Open AccessFile51 Downloads (Pure) -
Assessing the Evidence for Causal Associations Between Body Mass Index, C-Reactive Protein, Depression, and Reported Trauma Using Mendelian Randomization
Palmos, A. B., Hübel, C., Lim, K. X., Hunjan, A. K., Coleman, J. R. I. & Breen, G., 17 Jan 2023, In: Biological Psychiatry Global Open Science. 3, 1, p. 110-118 9 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Common and rare variant associations with latent traits underlying depression, bipolar disorder, and schizophrenia
Dattani, S., Sham, P. C., Jermy, B. S., Coleman, J. R. I., Howard, D. M. & Lewis, C. M., Dec 2023, In: Translational psychiatry. 13, 1, 46.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
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Esteban Tato NIHR Pre-doctoral Fellowship
Breen, G. (Primary Investigator) & Coleman, J. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/09/2023 → 31/08/2025
Project: Research
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Maudsley BRC: NIHR SLaM BRC
Hotopf, M. (Primary Investigator), Brose, L. (Co-Investigator), Brown, J. (Co-Investigator), Chalder, T. (Co-Investigator), Cleare, A. (Co-Investigator), Coleman, J. (Co-Investigator), Cunningham, J. (Co-Investigator), Dazzan, P. (Co-Investigator), Deluca, P. (Co-Investigator), Desrivieres, S. (Co-Investigator), Di Forti, M. (Co-Investigator), Dobson, R. (Co-Investigator), Drummond, C. (Co-Investigator), Dutta, R. (Co-Investigator), Egerton, A. (Co-Investigator), Emsley, R. (Co-Investigator), Gilchrist, G. (Co-Investigator), Gillett, A. (Co-Investigator), Goadsby, P. (Co-Investigator), Happe, F. (Co-Investigator), Hirsch, C. (Co-Investigator), Hoffmann, J. (Co-Investigator), Ismail, K. (Co-Investigator), Koutsouleris, N. (Co-Investigator), Lewis, C. (Co-Investigator), Marsden, J. (Co-Investigator), McAlonan, G. (Co-Investigator), McNeill, A. (Co-Investigator), Mehta, M. (Co-Investigator), Mondelli, V. (Co-Investigator), Moran, R. (Co-Investigator), Moss-Morris, R. (Co-Investigator), Neale, J. (Co-Investigator), Pariante, C. (Co-Investigator), Pile, V. (Co-Investigator), Powell, T. (Co-Investigator), Robson, D. (Co-Investigator), Rucker, J. (Co-Investigator), Schmidt, U. (Co-Investigator), Sonuga-Barke, E. (Co-Investigator), Stahl, D. (Co-Investigator), Stewart, R. (Co-Investigator), Strang, J. (Co-Investigator), Sweeney, A. (Co-Investigator), Turkheimer, F. (Co-Investigator), Vassos, E. (Co-Investigator), Wong, C. (Co-Investigator), Wykes, T. (Co-Investigator), Young, A. (Co-Investigator), Zahn, R. (Co-Investigator) & Zelaya, F. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/12/2022 → 30/11/2027
Project: Research
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Integrating polygenic risk scores with clinical drug development
Lewis, C. (Primary Investigator) & Coleman, J. (Co-Investigator)
1/10/2022 → 30/09/2026
Project: Research
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Identifying Common and Structural Genetic Variants Driving Genetic Associations with Major Depressive Disorder
Coleman, J. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)
1/05/2022 → 30/04/2024
Project: Research
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Applying and Refining Brain-specific Annotations to Interpret Psychiatric Genome-wide Association Study Results
Coleman, J. (Primary Investigator)
Brain and Behavior Research Foundation
15/01/2022 → 14/07/2024
Project: Research
Datasets
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R code for a latent class analysis of the UK Biobank data
Yapp, E., Davis, K., Coleman, J. & Booth, T., King's College London, 1 Jun 2020
DOI: 10.18742/rdm01-603, https://kcl.figshare.com/articles/software/R_code_for_a_latent_class_analysis_of_the_UK_Biobank_data/16473912
Dataset
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R code for a latent class analysis of the UK Biobank data (Version 2)
Yapp, E., Davis, K., Coleman, J. & Booth, T., King's College London, 15 Apr 2021
DOI: 10.18742/rdm01-727, https://kcl.figshare.com/articles/software/R_code_for_a_latent_class_analysis_of_the_UK_Biobank_data_Version_2_/16473960
Dataset