NIHR Biomedical Research Centre

Afzali, Ben (Primary Investigator)
Antoniou, Michael (Primary Investigator)
Barker, Jonathan (Primary Investigator)
Barratt, Benjamin (Primary Investigator)
Beighton, David (Primary Investigator)
Bevan, Stuart (Primary Investigator)
Blower, Philip (Primary Investigator)
Burchell, Joy (Primary Investigator)
Cason, John (Primary Investigator)
Chappell, Lucy (Primary Investigator)
Cope, Andrew (Primary Investigator)
Corrigan, Christopher (Primary Investigator)
Cunninghame Graham, Deborah (Primary Investigator)
Dontu, Gabriela (Primary Investigator)
Edgeworth, Jonathan (Primary Investigator)
Farzaneh, Farzin (Primary Investigator)
Gee, Tony (Primary Investigator)
Gould, Hannah (Primary Investigator)
Green, Peter (Primary Investigator)
Greenough, Anne (Primary Investigator)
Grigoriadis, Anita (Primary Investigator)
Hayday, Adrian (Primary Investigator)
Higginson, Irene (Primary Investigator)
Kalra, Lalit (Primary Investigator)
Karagiannis, Sophia (Primary Investigator)
Kelly, Frank (Primary Investigator)
Kemper, Claudia (Primary Investigator)
Lau-Walker, Margaret (Primary Investigator)
Lavender, Paul (Primary Investigator)
Lee, Tak (Primary Investigator)
Lempp, Heidi (Primary Investigator)
Lewis, Cathryn (Primary Investigator)
Lombardi, Giovanna (Primary Investigator)
Lord, Graham (Primary Investigator)
Marber, Michael (Primary Investigator)
Mason, James (Primary Investigator)
Mathew, Christopher (Primary Investigator)
McGrath, John (Primary Investigator)
Metcalfe, Alison (Primary Investigator)
Molokhia, Mariam (Primary Investigator)
Mullen, Gregory (Primary Investigator)
Nagel, Eike (Primary Investigator)
Neil, Stuart (Primary Investigator)
Nestle, Frank (Primary Investigator)
Oakey, Rebecca (Primary Investigator)
Parker, Peter (Primary Investigator)
Peakman, Mark (Primary Investigator)
Perera, Divaka (Primary Investigator)
Purushotham, Arnie (Primary Investigator)
Rasekh Ahmadi, Kourosh (Primary Investigator)
Rashid, Tamir (Primary Investigator)
Razavi, Reza (Primary Investigator)
Ridley, Anne (Primary Investigator)
Robson, Michael (Primary Investigator)
Sacks, Steven (Primary Investigator)
Sanchez Fueyo, Alberto (Primary Investigator)
Santis, George (Primary Investigator)
Sanz Moreno, Vicky (Primary Investigator)
Sawyer, Elinor (Primary Investigator)
Schaeffter, Tobias (Primary Investigator)
Shah, Ajay (Primary Investigator)
Sharpe, Paul (Primary Investigator)
Simpson, Michael (Primary Investigator)
Smith, Richard (Primary Investigator)
Sorinola, Isaac (Primary Investigator)
Spector, Tim (Primary Investigator)
Spicer, James (Primary Investigator)
Taams, Leonie (Primary Investigator)
Tavassoli, Mahvash (Primary Investigator)
Taylor, David (Primary Investigator)
Tree, Timothy (Primary Investigator)
Trembath, Richard (Primary Investigator)
Tribe, Rachel (Primary Investigator)
Tutt, Andrew (Primary Investigator)
Waltham, Matthew (Primary Investigator)
Watt, Fiona (Primary Investigator)
Webb, Andrew (Primary Investigator)
Wells, Claire (Primary Investigator)
Whelan, Kevin (Primary Investigator)
Whitaker, John (Primary Investigator)
Whittlesea, Cate (Primary Investigator)
Williamson, Catherine (Primary Investigator)
Wolfe, Charles (Primary Investigator)
Yu, Veronica (Primary Investigator)
academic, affiliated (Primary Investigator)
Hughes, Simon (Co-Investigator)
Montana, Giovanni (Co-Investigator)
Rhode, Kawal (Co-Investigator)
Schnabel, Julia (Co-Investigator)
Tziotzios, Christos (Co-Investigator)

Project: Research

Status	Finished
Effective start/end date	1/04/2007 → 31/03/2017

Collaborative partners

King's College London (lead)
GSTT Guy's and St Thomas' NHS Foundation Trust
Becton, Dickinson & Company
NIHR National Institute For Health & Care Research
St George's, University of London

Funding

DHSC Department of Health and Social Care: £8,755,130.00
DHSC Department of Health and Social Care: £1,581,100.00
NIHR National Institute For Health & Care Research: £14,203,500.00

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

4 Article
1 Review article

Identification of a transcription factor network regulating anti-TNF mediated IL10 expression in human CD4+ T cells
Povoleri, G., Ridley, M., Marrow, R., Lalnunhlimi, S., Ryan, S., Kelly, A., Lavender, P. & Taams, L., 27 Jul 2024, In: Discovery Immunology. 3, 1, kyae013.
Research output: Contribution to journal › Article › peer-review

Open Access
miR-155 overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T cell activation
Olsson, B. A., Povoleri, G., Somma, D., Ridley, M., Rizou, T., Lalnunhlimi, S., Macdonald, L., Rajasekhar, M., Martinez Nunez, R., Kurowska-Stolarska, M. & Taams, L., 30 Nov 2021, (E-pub ahead of print) In: Clinical and Expentmental Immunology.
Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus)
IKZF3/AIOLOs is associated with but not ₊sufficient _{T cells} for the expression of IL-10 by CD4: IKZF3 is associated with IL-10+ CD4+ T cells
Ridley, M., Fleskens, V., Roberts, C., Lalnunhlimi, S., Asnesf, A., O'Byrne, A., Steel, K., Povoleri, G., Sumner, J., Lavender, P. & Taams, L., 1 Jun 2020, In: Journal of Immunology. 204, 11, p. 2940-2948 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
18 Citations (Scopus)

130 Downloads (Pure)

1 Participation in conference

Annual European Congress of rheumatology (EULAR 2020)
Taams, L. (Invited speaker)
3 Jun 2020 → 6 Jun 2020
Activity: Participating in or organising an event › Participation in conference

NIHR Biomedical Research Centre

Project Details

Collaborative partners

Funding

UN Sustainable Development Goals

Fingerprint

Identification of a transcription factor network regulating anti-TNF mediated IL10 expression in human CD4+ T cells

miR-155 overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T cell activation

IKZF3/AIOLOs is associated with but not ₊sufficient _{T cells} for the expression of IL-10 by CD4: IKZF3 is associated with IL-10+ CD4+ T cells

Annual European Congress of rheumatology (EULAR 2020)

NIHR Biomedical Research Centre

Project Details

Collaborative partners

Funding

UN Sustainable Development Goals

Fingerprint

Research output

Identification of a transcription factor network regulating anti-TNF mediated IL10 expression in human CD4+ T cells

miR-155 overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T cell activation

IKZF3/AIOLOs is associated with but not +sufficient T cells for the expression of IL-10 by CD4: IKZF3 is associated with IL-10+ CD4+ T cells

Activities

Annual European Congress of rheumatology (EULAR 2020)

IKZF3/AIOLOs is associated with but not ₊sufficient _{T cells} for the expression of IL-10 by CD4: IKZF3 is associated with IL-10+ CD4+ T cells